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High PTH (parathyroid hormone) condition is called Hyperparathyroidism.
The parathyroid glands is found in neck behind thyroid gland infront of voice box in neck. It makes PTH hormone which maintains proper levels of both calcium and phosphorus in your body by turning the secretion of parathyroid hormone (PTH) off when calcium level in blood increasesand secretion of PTH increase whenever calcium level fall in blood due to any cause, much like a thermostat controls a heating system to maintain a constant air temperature.
Normally, this balancing act works well. When calcium levels in your blood fall too low, your parathyroid glands secrete enough PTH to restore the balance. PTH raises calcium levels by releasing calcium from your bones and increasing the amount of calcium absorbed from your small intestine.
When blood-calcium levels are too high, the parathyroid glands produce less PTH. The mineral calcium is best known for its role in keeping your teeth and bones healthy. But calcium has other functions. It aids in the transmission of signals in nerve cells, and it's involved in muscle contraction. Phosphorus, another mineral, works in conjunction with calcium in these areas.
CAUSES OF HIGH PTH
calcium deficiency. Your
body may not get enough calcium from your diet, often because your
digestive system doesn't absorb the calcium from it.
· Severe vitamin D deficiency. Vitamin D helps maintain appropriate levels of calcium in the blood, and it helps your digestive system absorb calcium from your food.
Your body produces vitamin D when your skin is exposed to sunlight, and you consume some vitamin D in food. If you don't get enough vitamin D, then calcium levels may drop.
· Chronic kidney failure. Your kidneys convert vitamin D into a form that your body can use. If your kidneys function poorly, usable vitamin D may decline and calcium levels drop. Chronic kidney failure is the most common cause of secondary hyperparathyroidism.
· Sometimes parathyroid start over functioning and starts making more pth hormone. This results in high calcium in blood, weak bones, kidney stone & gastric ulcer, decrease sleep anxiety etc may occur
First of all proper diagnosis for cause of high PTHneed to made by investigation and correct diagnosis. The treatment is in form of vitamin D and calcium supplement, correction of the basic cause found and other pth receptor modulators are given.
Most patients can be permanently cured time
What Is Hyperparathyroidism?
Hyperparathyroidism occurs when the parathyroid
glands make too much parathyroid hormone (PTH). The parathyroid glands are
four pea-sized endocrine glands located in your neck, near or attached to
the back of your thyroid. Endocrine glands secrete hormones necessary for
the normal functioning of the body.
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